Biochemical Composition and Anticancer Effect of Different Seaweed Species (In-vitro and In-vivo Studies)
Copyright © 2020 T H Ranahewa, A. D. Premarathna, R.M. K.K. Wijesundara, V. Wijewardana, A. P. Jayasooriya, R.P. V.J. Rajapakse. Published by Nan Yang Academy of Sciences Pte. Ltd.
This is an open access article under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) License.
Abstract
Seaweed is an enormous resource comprised with natural bioactive compounds with several therapeutic effects including anticancer activity. In this context, the biochemical composition of seaweed plays a major role. Many biochemical compounds isolated from seaweed, fractions of seaweed and crude extracts has revealed ability of seaweed to fight against several cancer types. In this contrast seaweed extracts inhibit cancer cell growth and proliferation by inducing apoptosis and by inhibiting metastasis activity. In this review, biochemical and anticancer properties of seaweeds are discussed and this will provide the basic information to develop a novel chemotherapeutic drug to challenge the cancers.
Keywords: Seaweed, Biochemical, Bioactive, Anticancer, Apoptosis